We are also developing a recombinant ‘S pseudo-typed lentivirus’ mimicking the Corona virus. This virus will be safe to work with even in BSL 2 laboratories. Since it has the spike protein on its surface, it can be used to aid new drug discoveries.
Syngene has also standardized an ELISA testing mechanism using the SARS-CoV2 S1 protein. Data generated for 350 healthy individuals and 35 confirmed COVID-19 positive individuals, indicates the high accuracy and specificity of the assays (> 95%).
Syngene has state-of-the-art protein analytics instrumentation to test the QC of each batch of reagent protein. This includes SDS-PAGE, Western blot, Analytical SE-HPLC, protein mass spec, binding studies using BIAcore and endotoxin analysis